Thursday, October 11, 2012

Enzyme Stories

Post your enzyme stories here.

4 comments:

  1. One fine day on Earth, as humans did their thing and Paul Ryan antagonized some interviewers, a strange airship landed on the plains of Spain (it was raining). A strange variety of creatures never before conceived of in the human imagination emerged from the have of fog.They approached a parked vehicle and addressed the teenagers inside in surprisingly fluent Spanish:
    "Ha combein por cinco?" extending five Euros in his very human-looking hand.
    "Um...Si" The bot said, ready to exchange currency. But when they touched hands, the strange creature latched onto his hand, intertwining fingers while a strange needle-spike stabed into the palm of the boys hand.
    "[Expletive]"
    The boy slumps, head hitting the steering wheel only a split second before the girl screams and scrambles for the door handle, only to be greeted with a smaller creature that drilled into the back of her neck, and made her go limp as the creature hit her spine.
    Word of aliens spread quickly through twitter and TV news. Studies of the creatures revealed that something they drew from the human immune system made them nearly invincible. Scientists named the dominant race the Substratta, the smaller creatures, CionHibbitors, and another race of creatures that seemed to have no apparent purpose, the Cofactas. The only immune were the elderly, the cancer victims, those with sickle cell anemia, due to their compromised body systems. Scientists scrambled to find a way to inhibit this, only to come up with a crude remedy: cut off everyone's fingers. It was a crude punishment for the vain human race, so use to their superiority; not even the scientists could bear to ask the humans to remove their thumbs. The lucky, wealthy enough to afford a part of diminished supply of anesthetic and have them surgically removed, while the less wealthy had to resort to more crude methods. As well, makeshift neck braces were used to inhibit the CoinHibbitors form causing a irreparable spinal damage.
    The Substratta spread across the globe, met with a strange combination of careful welcome from nations like the US and hostility from another, more cautious ones. Soon their rampage warranted a full-scale military attack. The Humans were winning, the hostiles made vulnerable by a lack of humans to exploit. However, things all changed once the seemingly docile cofactas revealed their true nature.
    They drew masses of humans to the dark corners of civilization, where the Substratta laid in wait. The human race was destroyed quietly; no one expected an alien invasion to happen under their noses. And thus, a race of now useless invincible aliens took Earth and all her IPhones.
    Products-invincible aliens
    Allosteric site-Back of neck
    Non Competitive inhibitors-neck braces
    Denaturation-Elderly, cancer patients, and sickle cell anemia sufferers.
    substrate-Substratta
    Enzyme-human race
    Cofactors-cofactas
    coenzymes-Neck Braces
    Activation energy-Alien invincibility

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    Replies
    1. What would be the active sit.
      e? What about feedback inhibition. I like your analogy, but you need to add to it.

      Coenzymes make the reaction happen better, not inhibit it.v
      Think about what activation energy is. Explain how alien invincibility would be like activation energy.

      Delete
  2. Hello There, Zombie Apocalypse
    The town of Vanceburg, KY fell silent as the citizens watched the local news in shock. The zombie apocalypse had begun and was nearing the small, hillbilly town. Most people began to panic and gathered their supplies while searching for hiding places. Even thought the town was in chaos, three brave souls were excited and ready to meet the challenge. Brooke, Dedre, and Laken grabbed the weapons that they had been storing for years and headed outside to meet the walking dead. It only took the zombies an hour to arrive after the news had been broadcasted. The lifeless bodies began walking toward the girls, so they began hacking away at their enemies from beyond the grave. The battle between these three brave girls and the zombies can be viewed just like the process of enzymes. The zombies, which are the attackers, would act as an enzyme, acting upon Brooke, Dedre, and Laken which are the substrates. The zombies (enzymes) use their mouths, which are their active sites, to bite the humans (substrates) and transform them into one of their own (product). the zombies put forth an immense amount of effort to change the humans and eat their flesh, which would be considered activation energy. Of course, the zombies couldn’t tear into the mundane flesh without the help of their cofactors, being their razor sharp teeth. They also possess strength in numbers when you consider all of the other zombies, acting as coenzymes. According to many frightened townspeople, the zombies cannot be stopped. Well, that is just nonsense! With the help of competitive inhibitors such as Dedre and Brooke shooting bullets into the zombie's mouth, they will stop it from biting a chunk out of Laken's flesh. Or, with the help of Laken taking an axe to the head of a zombie, Brooke and Dedre could escape a close call, thanks to Laken taking advantage of the zombie's allosteric site. The girls know that they have to kill and denature the zombies as fast as they can. They each pick up an axe and begin chopping off the undead extremities. The axe could act as the heavy metal salt, due to the fact that its ions will deform the active site. The girl's could also denature the zombies by torching them, which would use heat energy, or they could throw acid to change the pH level, which would also denature the enzyme by deforming the active site. Whenever the human race is wiped out and all become zombies, there will be no more humans left to convert, which will result in the feedback inhibition of zombies biting zombies because they are all out of humans. But hopefully, Brooke, Dedre, and Laken will prevail, and prevent the world from annihilation! 

    Brooke Dunigan and Dedre Bonner

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  3. Ruining Christmas: Grinch Style
    By: Kaitlyn Goodwin and Racheal Harlow
    Twas the night before Christmas, Tozyme was fast asleep in his warm bed; dreaming of Christmas, waking early to run down the stairs to find substrates under the tree and an empty platter and a glass half full. Running to the tree Tozyme dropped to his knees opening his gifts as is parents smiled with glee. Tozyme grabs each substrate, making Tozyme’s hands the active site, the gift wrappings and the bow on the substrate act as cofactors and coenzymes binding to Tozyme, as they fit perfectly around his gentle fingers. Tozyme’s beliefs in Activation Santa gave him the energy to unwrap the substrates quickly and efficiently revealing what’s inside. With Tozyme dreaming of substrates and Activation Santa, everything was functioning properly; it produced the product of a perfect Christmas.
    Meanwhile, the Grinch had his own dastardly plans to inhibit Tozyme and the perfect Christmas. He crept down the chimney, and then using a giant vacuum to block the substrates from fitting into the active site. Using the giant vacuum the Grinch swooped up all the substrates from under the tree and the one substrate Tozyme already had in his hands, ripping the substrate from his hands, pain shot down Tozyme’s arm and into his hands allowing the active site to become deformed, inhibiting in a competitive way.
    Becoming confident, the Grinch wanted to torture Tozyme by binding his hands, changing the active site’s shape leaving the substrates unable to fit in Tozyme’s hands, inhibiting in a noncompetitive way. The Grinch’s actions cause Tozyme’s perfect Christmas to denature in front of him. But Tozyme’s ruined Christmas is far from over as feedback inhibition occurs sweeping the substrates from the tree and from Tozymes, inhibiting in a competitive-like way, controlling the metabolism and allowing Tozyme’s product to be a ruined Christmas.

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